The diagnostic landscape of diffuse large B cell lymphoma of the mandible: A case report

Main Article Content

Dr. Jesline Rupa

Abstract

Lymphomas are a class of invasive haematopoietic malignancy constituting 2.2% of all humours of the head and neck. Two major set of lymphomas are Hodgkin’s lymphoma and non Hodgkin’s lymphoma (NHL) of which 90% are of the NHL group. The most frequently occuring NHL in the oral cavity is Diffuse Large B Cell Lymphoma (DLBCL) which involves waldeyer’s ring, base of the tongue, buccal mucosa and hard palate. This paper underscores a case report of DLBCL complications and the characteristic features  which contributed to the diagnosis.

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How to Cite
Dr. Jesline Rupa. (2023). The diagnostic landscape of diffuse large B cell lymphoma of the mandible: A case report. International Journal of Head and Neck Pathology, 6(1), 13–17. https://doi.org/10.56501/intjheadneckpathol.v6i1.834
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References

Bhattacharyya I, Chehal HK, Cohen DM, Al-Quran SZ. Primary diffuse large B cell lymphoma of the oral cavity: Germinal center classification. Head Neck Pathol 2010;4:181-91.

Braaten KM, Betensky RA, de Leval L, Okada Y, Hochberg FH, Louis DN, et al. BCL-6 expression predicts improved survival in patients with primary central nervous system lymphoma. Clin Cancer Res 2003;9:1063-9.

Guevara -Canales JO, Morales-Vadillo R, de Faria PE, Sacsaquispe-Contreras SJ, Leite FP, Chaves MG, et al. Systematic review of lymphoma in oral cavity and maxillofacial region. Acta OdontolLatinoam 2011;24:245-50.

Guevara-Canales JO, Morales-Vadillo R, Sacsaquispe-Contreras SJ, Barrionuevo-Cornejo C, Montes-Gil J, Cava-Vergiú CE, et al. Malignant lymphoma of the oral cavity and the maxillofacial region: Overall survival prognostic factors. Med Oral Patol Oral Cir Bucal 2013;18:e619-26.

He X, Chen Z, Fu T, Jin X, Yu T, Liang Y, et al. Ki-67 is a valuable prognostic predictor of lymphoma but its utility varies in lymphoma subtypes: Evidence from a systematic meta-analysis. BMC Cancer 2014;14:153

Horning SJ, Weller E, Kim K, Earle JD, O’Connell MJ, Habermann TM, et al. Chemotherapy with or without radiotherapy in limited-stage diffuse aggressive non-Hodgkin’s lymphoma: Eastern Cooperative Oncology Group study 1484. J Clin Oncol. 2004;22:3032-8

Kirita T, Ohgi K, Shimooka H, Okamoto M, Yamanaka Y, Sugmura M. Primary non-Hodgkin’s lymphoma of the mandible treated with radiotherapy, chemotherapy, and autologous peripheral blood stem cell transplantation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000;90:450-5

Rizzo K, Nassiri M. Diagnostic workshop of small B cell lymphomas: A laboratory perspective. Lymphoma 2012;1-15.

Sehn LH, Gascoyne RD. Diffuse large B-cell lymphoma: Optimizing outcome in the context of clinical and biologic heterogeneity. Blood 2015;125:22-32

Swerdlow SH, Campo E, Pileri SA, Harris NL, Stein H, Siebert R, et al. The 2016 revision of the world health organization classification of lymphoid neoplasms. Blood 2016;127:2375-90.