Effects of Diovan Hypertensive Medication on Oral manifestations (with and without smoker)

Thaer Kassim Ali; Raid Razak Ali AL-Kafaji

doi:10.56501/intjclinicopatholcorrel.v8i1.1042

Authors

Thaer Kassim Ali Department of Oral and maxillo facial histopathology, College of Dentistry, University of Kerbala, 56001, Karbala, Iraq
Raid Razak Ali AL-Kafaji Department of Oral and maxillo facial histopathology, College of Dentistry, University of Kerbala, 56001, Karbala, Iraq

DOI:

https://doi.org/10.56501/intjclinicopatholcorrel.v8i1.1042

Keywords:

High blood pressure, Cardiovascular Disease, Hypertensive Medications, Side effects

Abstract

High blood pressure is regarded as a general cardiovascular disease. Some hypertensive medications have several oral side effects. Hypertension is a chronic medical disorder, which widespread for the aging individuals. The ratio male to female was (1.19:1) for 90 cases with mean age (47.58). The highest frequency is (28) (46.70 %) of both periodontitis and dry mouth and followed by (14) (23.3 %) of periodontitis. Oral side effects are inevitable in hypertension patients that taking Diovan drugs and the most patients are not potential to convert or reduce the medications dose. Consequently, fixed dental investigations and soothing treatment may show a vital key in enhancing the patients' quality of life. Moreover, the chief oral manifestations found in hypertensive patient were periodontitis.

References

Negrini TdC, Carlos IZ, Duque C, Caiaffa KS, Arthur RA. Interplay among the oral microbiome, oral cavity conditions, the host immune response, diabetes mellitus, and its associated-risk factors—An overview. Frontiers in oral health. 2021;2:697428. https://doi.org/10.3389/froh.2021.697428

Chaudhry S, Bryant TK, Peeler CE. Venous sinus stenting in idiopathic intracranial hypertension: a safer surgical approach? Current Opinion in Ophthalmology. 2016;27(6):481-5.https://doi.org/10.1097/ICU.0000000000000315

Southerland JH, Gill DG, Gangula PR, Halpern LR, Cardona CY, Mouton CP. Dental management in patients with hypertension: challenges and solutions. Clinical, cosmetic and investigational dentistry. 2016;8(1):111-20. https://doi.org/10.2147/CCIDE.S99446

Northridge ME, Kumar A, Kaur R. Disparities in access to oral health care. Annual review of public health. 2020;41:513-35. https://doi.org/10.1146/annurev-publhealth-040119-094318

Del Pinto R, Landi L, Grassi G, Sforza NM, Cairo F, Citterio F, et al. Hypertension and periodontitis: A joint report by the Italian society of hypertension (SIIA) and the Italian society of periodontology and implantology (SIdP). High Blood Pressure & Cardiovascular Prevention. 2021;28:427-38. https://doi.org/10.1007/s40292-021-00466-6

Aliko A, Wolff A, Dawes C, Aframian D, Proctor G, Ekström J, et al. World Workshop on Oral Medicine VI: clinical implications of medication-induced salivary gland dysfunction. Oral surgery, oral medicine, oral pathology and oral radiology. 2015;120(2):185-206. https://doi.org/10.1016/j.oooo.2014.10.027

Islam NM, Bhattacharyya I, Cohen DM. Common oral manifestations of systemic disease. Otolaryngologic Clinics of North America. 2011;44(1):161-82. https://doi.org/10.1016/j.otc.2010.09.006

AlMudaris IZ, AlRawi NA. Salivary Matrix Metalloproteinase-8 (MMP-8) in Relation to Periodontal Health Status Among a Group of Hypertensive Patients. Journal of baghdad college of dentistry. 2018;30(3):48-53. https://doi.org/10.26477/jbcd.v30i3.2531

Di Spirito F, Iacono VJ, Alfredo I, Alessandra A, Sbordone L, Lanza A. Evidence-based recommendations on periodontal practice and the management of periodontal patients during and after the COVID-19 era: Challenging infectious diseases spread by airborne transmission. The Open Dentistry Journal. 2021;15(1). https://doi.org/10.2174/1874210602115010325

Aguayo S, Schuh CMAP, Vicente B, Aguayo LG. Association between Alzheimer’s disease and oral and gut microbiota: are pore forming proteins the missing link? Journal of Alzheimer's Disease. 2018;65(1):29-46. https://doi.org/10.3233/JAD-180319

Kumar P, Mastan K, Chowdhary R, Shanmugam K. Oral manifestations in hypertensive patients: A clinical study. Journal of Oral and Maxillofacial Pathology. 2012;16(2):215. https://doi.org/10.4103/0973-029X.99069

Tamura T, Kadomatsu Y, Tsukamoto M, Okada R, Sasakabe T, Kawai S, et al. Association of exposure level to passive smoking with hypertension among lifetime nonsmokers in Japan: a cross-sectional study. Medicine. 2018;97(48):e13241. https://doi.org/10.1097/MD.0000000000013241

Bosînceanu DG, Bida C, Marţu I, Forna DA, Baciu ER, Ciocan-Pendefunda AA, et al. Oral changes in a group of patients with High Blood pressure-Clinical Trial. Romanian Journal of Medical and Dental Education. 2018;7(2):64-7.

Maĭborodin I, Kolmakova I, Pritchina I, Chupina V. Changes in gum in cases of arterial hypertension combination with periodontitis. Stomatologiia. 2005;84(6):15-9.

Knight ET, Liu J, Seymour GJ, Faggion Jr CM, Cullinan MP. Risk factors that may modify the innate and adaptive immune responses in periodontal diseases. Periodontology 2000. 2016;71(1):22-51. https://doi.org/10.1111/prd.12110

Pralhad S, Thomas B, Kushtagi P. Periodontal disease and pregnancy hypertension: a clinical correlation. Journal of periodontology. 2013;84(8):1118-25. https://doi.org/10.1902/jop.2012.120264

Turner MD. Hyposalivation and xerostomia: etiology, complications, and medical management. Dental Clinics. 2016;60(2):435-43. https://doi.org/10.1016/j.cden.2015.11.003

Elmi Rankohi Z, Shabanian M, Maleki D. Oral Manifestations of Patients Taking Anti-Hypertensive Medications. Journal of Iranian Dental Association. 2020;32(3):83-8. https://doi.org/10.30699/jidai.32.3.4.83

Carrozzo M, Porter S, Mercadante V, Fedele S. Oral lichen planus: A disease or a spectrum of tissue reactions? Types, causes, diagnostic algorhythms, prognosis, management strategies. Periodontology 2000. 2019;80(1):105-25. https://doi.org/10.1111/prd.12260

Agrawal AA. Gingival enlargements: Differential diagnosis and review of literature. World Journal of Clinical Cases: WJCC. 2015;3(9):779. https://doi.org/10.12998/wjcc.v3.i9.779

Seol GH, Lee YH, Kang P, You JH, Park M, Min SS. Randomized controlled trial for Salvia sclarea or Lavandula angustifolia: differential effects on blood pressure in female patients with urinary incontinence undergoing urodynamic examination. The journal of alternative and complementary medicine. 2013;19(7):664-70. https://doi.org/10.1089/acm.2012.0148

Singh MV, Chapleau MW, Harwani SC, Abboud FM. The immune system and hypertension. Immunologic research. 2014;59(1):243-53. https://doi.org/10.1007/s12026-014-8548-6

Feihl F, Liaudet L, Waeber B. The macrocirculation and microcirculation of hypertension. Current hypertension reports. 2009;11(3):182-9. https://doi.org/10.1007/s11906-009-0033-6